Clinical Manifestations and Treatment of Idiopathic and Wegener Granulomatosis–Associated Subglottic Stenosis

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Clinical manifestations and treatment of idiopathic and Wegener granulomatosis-associated subglottic stenosis.

OBJECTIVE To compare and contrast the manifestations and surgical management of subglottic stenosis in patients with airway obstruction attributed to granulomatosis with polyangiitis (GPA), previously known as Wegener granulomatosis, and those with idiopathic subglottic stenosis (iSGS). DESIGN Retrospective medical chart review. Review of subglottic stenosis cases seen in the otolaryngology d...

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Disease homogeneity and treatment heterogeneity in idiopathic subglottic stenosis.

OBJECTIVES/HYPOTHESIS Idiopathic subglottic stenosis (iSGS) is a rare and potentially life-threatening disease marked by recurrent and progressive airway obstruction frequently requiring repeated surgery to stabilize the airway. Unknown etiology and low disease prevalence have limited the ability to characterize the natural history of iSGS and resulted in variability in surgical management. It ...

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Idiopathic Subglottic Tracheal Stenosis in Identical Twin Sisters

Introduction: Idiopathic subglottic tracheal stenosis is a rare inflammatory disease of the trachea; most commonly affects females within the age range of 20-50 years. No etiologic factor has yet been identified for this rare tracheal disease and therefore it should be diagnosed after the exclusion of other inflammatory, traumatic, and autoimmune diseases of the trachea. The familial or g...

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Idiopathic subglottic stenosis: an evolving therapeutic algorithm.

OBJECTIVES/HYPOTHESIS Idiopathic subglottic stenosis (ISS) is a rare type of airway stenosis of unclear etiology. Open resection, while effective, remains a complex surgery and requires a hospital stay. Endoscopic management is often preferred but has historically been associated with a high recurrence rate. We aimed to analyze our experience, consisting of a standardized endoscopic approach co...

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ژورنال

عنوان ژورنال: JAMA Otolaryngology–Head & Neck Surgery

سال: 2013

ISSN: 2168-6181

DOI: 10.1001/jamaoto.2013.1135